Creatine during bleeding anemia of rabbits
Syllm-Rapoport, I.; Dumdey, E.; Rapoport, S.
Acta Biologica et Medica Germanica 36(3-4): 411-414
1977
ISSN/ISBN: 0001-5318 PMID: 596054 Document Number: 119105
In bleeding induced anemia of rabbits an increase of creatine in the red cells occurred, which in some cases amounted to more than 5-times the normal concentration. In all but one case plasma creatine rose as well. Reticulocytosis, increased O2-consumption of the red cells and an increased level of erythropoietin indicated active erythropoiesis and a shift towards a younger cell population. Whether the rise of red cell creatine is solely due to a higher proportion of young cells remains an open question.
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