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Adenosine diphosphate-induced platelet aggregation in the states of hypercoagulability

Wang, T.Y.; Hussey, C.V.

Annals of Clinical and Laboratory Science 7(2): 152-157

1977

ISSN/ISBN: 0091-7370
PMID: 851349
Document Number: 117569
One hundred and seven patients with congestive heart failure, myocardial infarction and arteriosclerotic heart disease were studied by adenosine diphosphate-induced platelet aggregation, fibrinogen levels and ethanol gelation test. Both increases and decreases in platelet aggregation were observed. A significantly high percentage of patients showed a decreased platelet aggregation which was especially marked in the more acute as opposed to the less acute phase. In addition, most patients exhibited a marked shift from abnormal to normal platelet aggregation or vise-versa within a short time period. This pattern of platelet aggregation suggests an active role of platelets in the states of hypercoagulability. The hypercoagulability of these patients was further substantiated by a high percentage of positive ethanol gelation tests and high fibrinogen levels.

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Lozinova, T.A.; Brzhexskaia, O.N.; Nedelina, O.S. 1997: On the nature of free radicals of adenosine diphosphate in redox system NADH-riboflavin-adenosine diphosphate Biofizika 42(6): 1173-1179
Müller, R.; Lebrach, F. 1980: Haemorheological role of platelet aggregation and hypercoagulability in microcirculation: therapeutical approach with pentoxifylline Pharmatherapeutica 2(6): 372-379
Dietmann, K.; Birkenheier, H.; Schaumann, W. 1970: Inhibition of induced thrombocyte aggregation by adenosine and adenosine derivatives. 2. Correlation between inhibition of aggregation and peripheral vasodilatation Arzneimittel-Forschung 20(11): 1749-1751
Bonaduce, D.; Palomba, E.; Meduri, A.; Martone, F. 1975: Biochemical studies of bovine hydatid fluid. XX. Determination of adenosine-phosphates (adenosine-5'-monophosphate, adenosine-5'-diphosphate, adenosine-5'-triphosphate) Bollettino della Societa Italiana di Biologia Sperimentale 51(13): 824-827
Lukienko, P.I. 1973: The effect of adenosine triphosphate, adenosine diphosphate, adenosine monophosphate, adenosine and adenine on animal resistance to acute hypoxia Farmakologiia i Toksikologiia 36(5): 618-620
Charuruks, N.; Krailadsiri, P.; Seghatchian, M.J. 1997: Effect of cold exposure on platelet concentrates: changes in platelet indices and aggregation states Journal of the Medical Association of Thailand 80(1): 56-62
Ditter, H.; Matthias, F.R.; Lasch, H.G. 1984: Comparison of sympathomimetic amines with collagen, calcium ionophor and adenosine diphosphate in their effects on thromboxane formation of human platelet rich plasma Folia Haematologica 111(6): 761-768
Armstrong, R.; May, J.A.; Lösche, W.; Heptinstall, S. 1995: Factors that contribute to spontaneous platelet aggregation and streptokinase-induced aggregation in whole blood Thrombosis and Haemostasis 73(2): 297-303
Haskel, E.J.; Agarwal, K.C.; Parks, R.E. 1980: ATP- and ADP-induced rat platelet aggregation: significance of plasma in ATP-induced aggregation Thrombosis and Haemostasis 42(5): 1580-1588
Guse, A.H.; da Silva, C.P.; Emmrich, F.; Ashamu, G.A.; Potter, B.V.; Mayr, G.W. 1995: Characterization of cyclic adenosine diphosphate-ribose-induced Ca2+ release in T lymphocyte cell lines Journal of Immunology 155(7): 3353-3359
Yi, F.X.; Guo, Z.G. 1998: Platelet-released ADP stabilizes PAF-induced rabbit platelet aggregation by stabilizing intracellular calcium Zhongguo Yao Li Xue Bao 19(4): 379-382
Appel, J.Z.; Alwayn, I.P.; Correa, L.E.; Cooper, D.K.; Robson, S.C. 2001: Modulation of platelet aggregation in baboons: implications for mixed chimerism in xenotransplantation. II. The effects of cyclophosphamide on pig peripheral blood progenitor cell-induced aggregation Transplantation 72(7): 1306-1310
Rossi, E.C.; Louis, G.; Bieber, M.; Zeller, E.A. 1978: Platelet monoamine oxidase and epinephrine-induced platelet aggregation Thrombosis and Haemostasis 40(1): 37-42
Nyby, M.D.; Sasaki, M.; Ideguchi, Y.; Wynne, H.E.; Hori, M.T.; Berger, M.E.; Golub, M.S.; Brickman, A.S.; Tuck, M.L. 1996: Platelet lipoxygenase inhibitors attenuate thrombin- and thromboxane mimetic-induced intracellular calcium mobilization and platelet aggregation Journal of Pharmacology and Experimental Therapeutics 278(2): 503-509
Bar, J.; Tepper, R.; Fuchs, J.; Pardo, Y.; Goldberger, S.; Ovadia, J. 1993: The effect of estrogen replacement therapy on platelet aggregation and adenosine triphosphate release in postmenopausal women Obstetrics and Gynecology 81(2): 261-264
Fiedel, B.A.; Simpson, R.M.; Gewurz, H. 1977: Effects of C-reactive protein on platelet function. III. the role of cAMP, contractile elements, and prostaglandin metabolism in CRP-induced inhibition of platelet aggregation and secretion Journal of Immunology 119(3): 877-882
Zahavi, M.; Zahavi, J.; Kakkar, V.V. 1984: Effect of adenyl-cyclase activators, phosphodiesterase inhibitors and pyridoxal-5-phosphate on platelet aggregation and adenosine-3'-5'-cyclic monophosphate accumulation Thrombosis and Haemostasis 52(2): 205-209
Karpatkin, S.; Ambrogio, C.; Pearlstein, E. 1988: The role of tumor-induced platelet aggregation, platelet adhesion and adhesive proteins in tumor metastasis Progress in Clinical and Biological Research 283: 585-606
Fuse, I.; Hattori, A.; Mito, M.; Higuchi, W.; Yahata, K.; Shibata, A.; Aizawa, Y. 1996: Pathogenetic analysis of five cases with a platelet disorder characterized by the absence of thromboxane A2 (TXA2)-induced platelet aggregation in spite of normal TXA2 binding activity Thrombosis and Haemostasis 76(6): 1080-1085
Perutelli, P.; Marchese, P.; Mori, P.G. 1992: Monoclonal antibody-induced platelet aggregation does not require interaction between antibody and platelet Fc receptor Haematologica 77(2): 186-187