Platelet monoamine oxidase and epinephrine-induced platelet aggregation
Rossi, E.C.; Louis, G.; Bieber, M.; Zeller, E.A.
Thrombosis and Haemostasis 40(1): 37-42
1978
ISSN/ISBN: 0340-6245 PMID: 725849 Document Number: 134113
Platelet MAO activity and the aggregation response to epinephrine, ADP, and collagen were measured in normal subjects. There was a direct correlation between the amount of platelet MAO activity and the per cent aggregation induced by 1 and 2 micrometer epinephrine. There were lesser correlations between platelet MAO and ADP or collagen-induced aggregation. These findings suggest that platelet MAO may play a role in determining the response of human platelets to epinephrine.