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Charge-transfer adsorption chromatography

Porath, J.; Caldwell, K.D.

Journal of Chromatography 133(1): 180-183

1977

ISSN/ISBN: 0021-9673
PMID: 838797
Document Number: 117018
The synthesis of dinitrophenylthioether-substituted Sephadex G-25 and Sepharose 6B gels is described. The dinitrophenylthio ligand is a .pi.-electron acceptor capable of forming charge-transfer complexes with electron-donor substances. The charge-transfer adsorption chromatography separation of a number of neurophysiologically important compounds including tryptamine, tryptophan, phenylalanine, serotonin, IAA, epinephrine, norepinephrine, L-dopa, mescaline, acetophenazine, fluphenazine and chlorpromazine is described.

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