Behavioral toxicology: effects of early postnatal exposure to neurotoxins on development of locomotor activity in the rat

Reiter, L.

Journal of Occupational Medicine. Official Publication of the Industrial Medical Association 19(3): 200-204

1977


ISSN/ISBN: 0096-1736
PMID: 839292
Document Number: 115394
Early postnatal treatment with various neurotoxins may produced behavioral alterations which are manifested only during certain periods of development. Results are presented on locomotor activity following Pb or mirex administration which indicate that although these toxins produce similar changes in behavior they have marked differences in their time-course. The extended observation of locomotor activity over several days allows the investigator to distinguish between a reactive locomotion and spontaneous locomotion.

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