Reactions of cardiomyocytes of the right half of the heart to trauma to the left
Bol'shakova, G.B.
Biulleten' Eksperimental'noi Biologii i Meditsiny 83(5): 610-612
1977
ISSN/ISBN: 0365-9615 PMID: 884272 Document Number: 114822
Myocardial infarction of the left ventricle was induced in adult rats weighing 120-160 g by ligation of the left coronary artery; the left atrium was injured in the second group of rats; the third group of the animals was subjected to the sham operation (only the pericardium was removed). On the 5th postoperative day the dividing myocytes were found in the right auricle (mitotic index varied from 0.7 to 8.8%) and in the subepicardial region of the right ventricle (mitotic index from 0.8 to 2.9%). On the third postoperative day the myocytes of the myocardium of senescent rats weighing 300-430 g proliferated in the left auricular appendage (mitotic index--from 1 to 5.1%) and in the right auricula appendage (in one of 8 cases, mitotic index 4.2%). Only rare mitoses were found in the subepicardial region of the left ventricle.