Erythrocytic changes in experimental myocardial infarct in dogs
Tarasov, A.N.; Loginova, T.G.
Kardiologiia 17(8): 130-133
1977
ISSN/ISBN: 0022-9040 PMID: 926557 Document Number: 114405
The nature and mechanisms of changes in the red blood in the acute period of myocardial infarction were studied. Focal necrosis of the myocardium was induced in 97 dogs by ligature of the left coronary artery or by thoracotomy without ligature. In the 1st day after the operation increases were noted in the number of erythrocytes, Hb and hematocrit, accompanied by an increase in the mass of red blood cells and reduction of their life span. Intensification of erythropoiesis in the acute period in conjunction with circulation impairment was possibly a compensatory reaction to O2 starvation of tissues. Normoblast and reticulocyte levels in bone marrow were also reduced.