Serum IgE levels in forty families studied for two or three years
Gerrard, J.W.; Brook, D.
Annals of Allergy 38(6): 396-399
1977
ISSN/ISBN: 0003-4738 PMID: 869300 Document Number: 114325
Serum IgE levels have been measured over two to three years in 210 individuals. In one-fifth IgE levels remained remarkably constant, in one-quarter they rose and in half they fell. A rise was usually associated with the development of fresh atopic disease, exacerbation of established disease or dependence on symptomatic treatment. A fall was associated with a diminution in the severity of symptoms occurring spontaneously as a result of good environmental control or of appropriate immunotherapy. Sequential IgE levels provide confirmatory evidence of the success of either environmental control or of immunotherapy.