Effects of serotonergic drugs on methaqualone-induced hypothermia
Boggan, W.O.; Meyer, J.S.
Research Communications in Chemical Pathology and Pharmacology 16(4): 629-636
1977
ISSN/ISBN: 0034-5164 PMID: 140451 Document Number: 113269
Methaqualone (75 mg/kg) produced a significant decrease in the rectal temperature of mice. This effect was antagonized by parachlorophenylalanine and potentiated by Lilly 110140. These compounds also decreased and increased respectively the circulating concentration of methaqualone.
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