Chemotherapy of human nervous system tumors: influence on cerebrospinal fluid sterols

Paoletti, P.; Pezzotta, S.; Racca, A.R.; Fumagalli, R.

National Cancer Institute Monograph 46: 125-126

1977


ISSN/ISBN: 0083-1921
PMID: 613223
Document Number: 112485
The cerebrospinal fluid levels of cholesterol, desmosterol, and the ratio 100 D:C taken from a study of 59 patients are reported. The patients, who had tumors of the nervous system, underwent neurosurgery, radiotherapy, and chemotherapy with 1,3-bis(2-chloroethyl)-1-nitrosourea or 1-(2-chlororethyl)-3-cyclohexyl-1-nitrosourea. The relationships among the levels of these three parameters and the clinical and neuroradiologic evolution are discussed.

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