Experiments on the mechanism of action of vascular spasmolytics. 4. Effect of nitroprusside sodium, nitroglycerin, prenylamine and verapamil on the calcium uptake of microsomes of the smooth bascular muscles
Klinner, U.; Ehlers, D.; Fermum, R.; Meisel, P.
Acta Biologica et Medica Germanica 36(7-8): 1143-1148
1977
ISSN/ISBN: 0001-5318 PMID: 417536 Document Number: 111881
Nitroprusside-sodium, nitroglycerol, and verapamil had no effect on the calcium uptake by microsomes from the carotid artery of cattle. Prenylamine reduced the passive binding and the active uptake and released already bound calcium. The basal Mg-dependendent ATPase and Ca-stimulatable Mg-ATPase were inhibited by prenylamine.