Automated Immunoassay for Reliable Measurement of Sex Hormone Binding Globulin (SHBG)
Gruson, D.; Maisin, D.; Fillee, C.
Clinical Laboratory 57(1-2): 87-90
2011
ISSN/ISBN: 1433-6510 PMID: 21391470 Document Number: 11118
Background: Sex hormone binding globulin (SHBG) is important for the transport and regulation of distribution of sex steroids. Methods: The performance of the Architect® SHBG automated immunoassay in comparison to radioimmunoassay was evaluated using 62 patient specimens. Furthermore, specimen from 100 healthy individuals were used to establish a preliminary reference interval for this automated assay. Results: The assay has demonstrated overall good analytical performance and was significantly correlated with the reference method. Conclusions: The Architect ® SHBG assay is a good method for routine measurement of SHBG circulating levels.
Document emailed within 1 workday
