Effect of psychostimulants on the relearning by rats of the avoidance direction in a U-shaped labyrinth
Baturin, V.A.
Biulleten' Eksperimental'noi Biologii i Meditsiny 81(5): 554-556
1976
ISSN/ISBN: 0365-9615 PMID: 947377 Document Number: 109985
The capacity of rats to relearning the direction of the avoidance in a U-shaped maxe was determined. Four traning sessions--each time in a new direction (to the right, or to the left) of running were conducted. D, 1-amphetamine given in low and medium doses (0.5 and 2 mg/kg) shortened the latent response periods and failed to influence the relearning of the animals. A high dose of the drug (5 mg/kg) led to reduction of the latency of the responses, but at the same time inhibited the reconstruction of the avoidance habit; this distinctly correlated with the intensification of space preference. Caffine (25 and 50 mg/kg) failed to influence the relearning of rats.