The pathogenesis of gastric carcinoma--epidemiologic pathology of precursor lesions
Correa, P.; Cuello, C.; Haenszel, W.
Leber Magen Darm 6(2): 72-79
1976
ISSN/ISBN: 0300-8622 PMID: 966935 Document Number: 108638
An overview of the epidemiologic and pathologic significance of premalignant lesions of the stomach is presented, with correlations between cancer risk, prevalence of atrophic gastritis and environmental factors such as nitrate and food items. The protective role of lettuce and fresh vegetables is discussed. The diffuse type of gastric cancer appears to be less environmentally linked than the intestinal type, and it is hypothesized that the pathogenetic process may begin during the first decade of life. An analysis of precursor lesions and gastric cancer in various geographic regions of Columbia, South America is presented to illustrate these relationships.