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Functional state of the spleen in conditions of craniocerebral hypothermia

Penner, S.D.

Biulleten' Eksperimental'noi Biologii i Meditsiny 81(5): 525-528

1976

ISSN/ISBN: 0365-9615
PMID: 947369
Document Number: 108105
Experiments were conducted on dogs. With the fall of body temperature from 36 to 24 degrees C the circulation volume of the spleen decreased from 53.9 +/- 1.94 to 17.9 +/- 0.84 ml/100 g/min, and the arterio-venous difference by oxyhemoglobin - from 19.5 +/- 0.58 to 3.3 +/- 0.23%. Marked body overcooling completely depressed the capacity of the spleen to extract low-resistant erythrocytes from the circulation. A fall of body temperature from 36 to 30 degrees C was accompanied by reduction of the splenic area to 92.6 +/- 2.6%; subsequent chilling led to the accumulation of blood in the pulp with increase of the organ area to 108.7 +/- 4.82%.

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