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Interaction of histones with human serum proteins

Lostický, C.; Jelínek, R.

Physiologia Bohemoslovaca 25(4): 341-344

1976

ISSN/ISBN: 0369-9463
PMID: 185637
Document Number: 107903
The authors describe the interactions of whole calf thymus histone and its fractions with the human serum proteins. Immunoelectrophoretic analysis revealed two types of interactions: 1) a decrease in the electrophoretic mobility of a whole, immunochemically uniform fraction, and 2) a decrease in the electrophoretic mobility of only some molecules of such a fraction. In this association, the arginine-rich histone fraction (F3) was found to be the most active. The findings are important for interpreting the results of biological treatments.

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