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Lactate dehydrogenase and glucose-6-phosphate dehydrogenase activity in the erythrocytes in diabetes mellitus

Drel', K.A.; Shelest, I.P.

Voprosy Meditsinskoi Khimii 22(4): 469-472

1976

ISSN/ISBN: 0042-8809
PMID: 1027230
Document Number: 107344
In human erythrocytes activities of glucose-6-phosphate and lactate dehydrogenases were decreased approximately 2-fold in moderately severe and critical forms of diabetes mellitus, as compared with normal state. The lactate dehydrogenase activity was more distinctly decreased than the glucose-6-phosphate dehydrogenase activity. General medical treatment increased the activity of the enzymes (which catalyzed the ATP formation in erythrocytes) and normalized their relation.

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