Deterioration in renal function in association with co-trimoxazole therapy

Bailey, R.R.; Little, P.J.

Medical Journal of Australia 1(24): 914 916

1976


ISSN/ISBN: 0025-729X
PMID: 979747
Document Number: 107095
Deterioration in renal function has been observed in four patients who were taking co-trimoxazole. Three patients had stable chronic renal failure, and in two of these there was a further permanent impairment of renal function. The remaining patient received co-trimoxazole while recovering from a short episode of acute oliguric renal failure. It is suggested that co-trimoxazole be withheld, or used with caution in patients with impaired renal function.

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