Peritoneal reaction to infection with tsutsugamushi rickettsia in mice with different sensitivity to the agent
Chyong-dinh-Kiet
Voprosy Virusologii 3: 366-371
1976
ISSN/ISBN: 0507-4088 PMID: 983005 Document Number: 106967
Infection of white random-bred mice and C57B1(6) mice with a culture of R. tsutsugamushi demonstrated that white mice were highly susceptible to the infection which ended in death of the animals and accumulation of rickettsia in the body and necrotization of cell elements of the exudate. Mice of C57B1(6) strain developed acymptomatic infection, rickettsia did not multiply in the peritoneal cavity and exudate cells did not undergo necribiosis. The mechanism of resistance of cells of these mice to the agent requires a further study.