A multiplexed 1,440 and 1,320 nm laser for treatment of chronic photodamage
Bernstein, E.F.
Journal of Drugs in Dermatology Jdd 10(11): 1266-1270
2011
ISSN/ISBN: 1545-9616 PMID: 22052306 Document Number: 10546
The purpose of this study is to quantify the safety and effectiveness of a multiplexed 1,440 and 1,320 nm fractionated laser for the treatment of chronic photodamage. A total of twenty subjects with chronic photodamage were enrolled in this study. Subjects received a maximum of four full-face treatments at an average fluence of 9.5 J/cm2 at 1,320 nm and 2 J/cm2 at 1,450 nm, delivered sequentially using forced-air cooling, at monthly intervals. Digital photographs were taken two months following the final treatment and compared to pre-treatment photographs by two blinded physician observers. Improvement in photodamage, overall appearance, wrinkles, hyper-pigmentation, enlarged pores, and sagging skin was rated by blinded physician evaluation of digital photographs as being in the 25-50 percent range. Subjective ratings averaged improved for all criteria that were evaluated, including wrinkles, enlarged pores, redness, sagging skin and hyper-pigmentation. The multiplexed 1,320 nm and 1,440 nm fractionated laser improves cutaneous photodamage as assessed by objective and subjective criteria.
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