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In vitro effect of serotonin on the enzyme activities of glutamate decarbosylase and GABA transaminase at the level of acellular preparations of rat mesencephalon synaptosomes

Belin, M.F.; Kouyoumdjian, J.C.; Gonnard, P.; Jouvet, M.

Comptes Rendus des Seances de la Societe de Biologie et de ses Filiales 170(6): 1243-1247

1976

ISSN/ISBN: 0037-9026
PMID: 140743
Document Number: 105229
The effect of serotonin on glutamate decarboxylase and GABA-transaminase was studied, in vitro, in synaptosome homogenates from rat mesencephalon. Serotonin dissolved in the incubation medium inhibits glutamate decarboxylase activity and stimulates GABA-transaminase activity.

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