Prediction of radiosensitivity of individual mice by multidimensional analysis
Sato, F.; Kawashima, N.; Nishimoto, Y.; Nakamura, W.
Folia Biologica 12(3): 209-216
1976
ISSN/ISBN: 0015-5500 PMID: 992151 Document Number: 104871
Ten physiological indices on each mouse were measured before an exposure to ionizing radiation. The exposure of mice to 700R of X-rays induced 45% mortality within 30 days. A prediction of death or life of each mouse was done by a multidimensional quantification. The highest success rate of prediction was obtained by using all ten indices and it resulted in 74.1%. Accordingly, it was possible to predict death of individual mice exposed to a dose around LD50 (30) with a high rate of success. When one selected five indices out of the ten indices by some criterion, the success rate of prediction decreased to 67.1%.