Topically applied antibiotics in acne vulgaris: clinical response and suppression of Corynebacterium acnes in open comedones
Resh, W.; Stoughton, R.B.
Archives of Dermatology 112(2): 182-184
1976
ISSN/ISBN: 0003-987X PMID: 134675 Document Number: 103919
Topical antibiotics were used on patients with acne vulgaris. Corynebacterium acnes organisms from open comedones were quantitated during treatment, and the progress of the disease was evaluated. Clindamycin lotion completely suppressed the growth of C acnes organisms, whereas erythromycin and tetracycline did not depress the C acnes counts. Taken as a group, these antibiotics gave a substantial improvement of the disease on the treated side as compared with paired untreated sides of the face and back.