Studies concerning dopamine diuresis in the rat
Pendleton, R.G.; Sherman, S.S.
Archives Internationales de Pharmacodynamie et de Therapie 222(1): 94-102
1976
ISSN/ISBN: 0003-9780 PMID: 10862 Document Number: 103587
Dopamine is both diuretic and saluretic in the conscious rat. The diuretic effect does not appear to be beta-receptor mediated, but rather may be the result of a combination of alpha- and dopaminergic receptor stimulation. Conclusive proof for the existence of the latter, however, must await the discovery of a more selective peripheral dopamine-receptor stimulant than is dopamine per se.
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