Understanding the Clinical Biochemistry of N-Terminal Pro-B-Type Natriuretic Peptide: the Prerequisite for Its Optimal Clinical Use

Panteghini, M.; Clerico, A.

Clinical Laboratory 50(5-6): 325-331

2004


ISSN/ISBN: 1433-6510
PMID: 15209441
Document Number: 10332
With the introduction of the first rapid, fully automated assay for N-terminal pro-B-type natriuretic peptide (NtproBNP) determination, clinical laboratories are now able to transfer a number of preliminary information derived from pilot research experiences to the context of clinical cardiology. Some confounding factors may, however, affect the interpretation of the Nt-proBNP test and its clinical value. The objective of this review is to highlight and discuss these potentially confounding variables.

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Understanding the Clinical Biochemistry of N-Terminal Pro-B-Type Natriuretic Peptide: the Prerequisite for Its Optimal Clinical Use