Effect of arecoline on synaptosomal K+-phosphatase and (Na+ + K+) -ATPase
Schwarzenfeld, I.; Blaschke, M.; Fischer, H.D.; Rudolph, E.; Oelszner, W.
Acta Biologica et Medica Germanica 35(1): 69-72
1976
ISSN/ISBN: 0001-5318 PMID: 185859 Document Number: 103026
Synaptosomal fractions and synaptosomal membranes from rat brain tissue were prepared and characterized enzymatically. Arecoline increased both the activity of K+-phosphatase in incubated synaptosomal fractions and the (Na+ + K+)-ATPase activity of synaptosomal membranes by 40% and 78%, respectively. This activation of ion transport processes is believed to be associated with increased ACh synthesis produced by arecoline.