Sequential combination chemotherapy for advanced, recurrent, squamous carcinoma of the head and neck

Livingston, R.B.; Einhorn, L.H.; Burgess, M.A.; Gottlieb, J.A.

Cancer Treatment Reports 60(1): 103-105

1976


ISSN/ISBN: 0361-5960
PMID: 63330
Document Number: 102983
Of the 28 patients with head and neck squamous cancer who had no prior chemotherapy, 12 (43%) had a > 50% regression and 5(18%) had complete clinical disappearance. The regimen used was cyclophosphamide-vincinstine-bleomycin, methotrexate and adriamycin-methyl 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea [CCNU] followed by methotrexate and adriamycin-methyl CCNU.

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