Study of bacterial allergy in acute appendicitis by the method of leukocyte migration inhibition in vitro
Shturich, P.I.; Novikov, D.K.; Adamenko, G.P.
Vestnik Khirurgii Imeni I. I. Grekova 116(4): 51-55
1976
ISSN/ISBN: 0042-4625 PMID: 785785 Document Number: 102830
Under study was the effect of various bacterial allergens on the migration of blood leucocytes from capillaries in vitro in 23 patients with acute appendicitis and in 18 healthy individuals. Bacterial allergens wound suppress leucocytes migration in all patients. Most frequently, sensibilization to allergens of hemolytic staphylococcus and hemolytic streptococcus was found. In 4 healthy persons this methods indicated sensibilization to some allergens. The interaction of activity sensibilized lymphocytes and passively sensibilized polynuclears of the appendix with bacterial antigens is assumed to tigger the hyperergic reaction in acute appendicitis.