The escape of bile from the intrhepatic biliary tree in acute bile stasis
Jakab, F.; Bloom, S.R.; Szabó, G.
Zeitschrift für Mikroskopisch-Anatomische Forschung 90(1): 200-205
1976
ISSN/ISBN: 0044-3107 PMID: 1020420 Document Number: 101905
The escape of fluorescent dyes from the bile passages during bile stasis and after a retrograde infusion into the common bile duct was examined in rats and mice. After an i.v. dye injection in bile stasis a strong fluorescence was seen in the periportal spaces. During retrograde dye infusion great amounts of dye accumulated in the periportal spaces but, in consequence of focal disruption of liver cell membranes, escapes into the spaces of Disse, to be consequently transported by the sinusoidal blood.