Blood leukocytes, with special reference to basophils and eosinophils, during provocation tests in fixed eruption and drug exanthema
Stubb, S.
Acta Dermato-Venereologica. Supplementum 56(76): 1-47
1976
ISSN/ISBN: 0365-8341 PMID: 134614 Document Number: 101897
A total of 186 drug provocations were performed on 160 patients over an 8 yr period to observe the clinical symptoms of the blood leukocytes, especially the basophils and eosinophils, during drug provocation. An attempt was made to ascertain whether the length of the period since the preceding eruption, the time at which the clinical symptoms appeared and the severity of the clinical symptoms had an effect on changes in the number of those cells. The decline in basophils in particular, but also in eosinophils during positive drug provocation tests suggest that these cells play an important role in drug eruptions of fixed eruption and exanthema types.