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Evaluation of a modified water-deprivation test for diagnosis of polyuric disorders in dogs

Mulnix, J.A.; Rijnberk, A.; Hendriks, H.J.

Journal of the American Veterinary Medical Association 169(12): 1327-1330

1976

ISSN/ISBN: 0003-1488
PMID: 1033931
Document Number: 101389
A modified water-deprivation test was performed on 12 polyuric and 4 clinically normal dogs. Immediately after maximal urine osmolality had been achieved with water deprivation, antidiuretic hormone was injected to test further renal concentrating ability. The test provided accurate diagnosis of severe hypothalamic-neurohypophyseal diabetes insipidus in 3 dogs, partial diabetes insipidus in 2 dogs, and primary (psychogenic) polydipsia in 2 dogs. Five polyuric dogs with hyperadrenocorticism had a response to the modified water-deprivation test similar to that of dogs with partial diabetes insipidus.

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