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Inhibiting effect of cholera vibrio neuraminidase in Rauscher mouse leukemia

Barinskiĭ, I.F.; Korbinskiĭ, G.D.

Biulleten' Eksperimental'noi Biologii i Meditsiny 82(11): 1357-1359

1976

ISSN/ISBN: 0365-9615
PMID: 1016719
Document Number: 99439
A study was made of the inhibitory effect of neuraminidase of cholera vibrio in mouse Rauscher leukemia. It was shown that the processing of cells of the spleen of mice suffering from leukemia with neuraminidase (in a dose of 50 units/ml and more) significantly inhibited the capacity of these cells to induce leukemia in their injection to BALB/c mice. In the mentioned concentration neuraminidase injected repeatedly parenterally produced no therapeutic effect in Rauscher leukemia.

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