Protein-analytical studies on the serum and urine of patients with visceral lupus erythematosus
Beenken, O.; Häntzschel, H.; Birkenmeier, G.; Pietruschka, W.D.; Otto, W.
Zeitschrift für die Gesamte Innere Medizin und ihre Grenzgebiete 31(6): 180-182
1976
ISSN/ISBN: 0044-2542 PMID: 60006 Document Number: 99003
Serum and urine of patients with ascertained lupus erythematodes visceralis were separated by means of the polyacrylamide gel pore gradient electrophoresis on the same experimental conditions. Deviations from the normal electropherogram were found in the serum within the gamma-globulins. For the demonstration of antinuclear factors the loose body test, the LE-cell test as well as the immunofluorescence test were carried out. In the uropherogram a highly molecular protein band could be proved which did not appear in the serum. In this fraction an immune complex which developed in the area of the kidney might be in question. It is referred to the possibility of the use of the PAA-polyacrylamide gel electrophoresis for the early recognition of renal changes.