Immunoglobulins in the CSF during meningitis
Humbert, G.; Meunier, M.; Delpech, B.; Pasquis, P.; Aubertin, J.; Leroy, J.
Pathologie-Biologie 24(10): 677-684
1976
ISSN/ISBN: 0369-8114 PMID: 796789 Document Number: 98888
Cerebrospinal fluid and serum immunoglobulins were studied in 76 patients with acute meningitis of various aetiologies. This comparative study showed that the increase of CSF immunoglobulin levels was related to important modifications of the permeability of the blood-brain barrier (especially in case of bacterial meningitis) or to a local in situ production (particularly in case of "viral" meningitis). Results obtained allow us to draw a different biochemical pattern in purulent meningitis and acute lymphocytic meningitis.