Liver tumors and oral contraceptives
Senanayake, P.
Ippf Medical Bulletin 10(2): 4
1976
ISSN/ISBN: 0019-0357 PMID: 12258767 Document Number: 97282
In the past 6 years there has been an increase in the number of published reports of women with benign hepatic adenomas who had also been taking oral contraceptives. There have been 80 such reports. In 3 instances, patients have developed malignant hepatomas while taking oral contraceptives. Several oral contraceptive compounds have been implicated. Duration of such therapy has varied from 6 months to over 5 years. Pain with a palpable abdominal mass has usually been present. Rupture of the tumor with hemorrhage into the peritoneal cavity has been the most serious complication. The small number of recorded cases and the large number of women who have taken oral contraceptives suggest that this is a relatively rare complication.