Predictors of non-significant endoscopic findings in patients with suspected upper gastrointestinal tract hemorrhage
Sumritpradit, P.; Tangkittimasak, S.; Lertsithichai, P.
Journal of the Medical Association of Thailand 88(9): 1207-1213
2005
ISSN/ISBN: 0125-2208 PMID: 16536106 Document Number: 9652
The objective of the present study was to determine pre-endoscopic predictive factors of nonsignificant endoscopic findings in patients with suspected upper gastrointestinal tract hemorrhage (UGIH). Medical records of 187 patients admitted with the primary diagnosis of UGIH were reviewed. Non-significant endoscopic findings were defined as "normal": "mild gastritis" or unspecified gastritis with a hospital stay of two days or less. Possible predictors of non-significant endoscopic findings included pertinent history, physical examination, nasogastric tube aspirate, routine laboratory findings, and units of infused packed red cells (PRC). Multiple logistic regression analysis was used to determine significant predictors. Predictors of non-significant endoscopic findings included the absence of comorbid diseases (OR: 6.4; 95%CI: 3.0-13.6), higher platelet count (OR. 1.7 per 100,000 increase; 95%CI: 1.1-2.5) and less PRC infusion (OR: 1.9 per unit decrease; 95%CI: 1.3-2.7). Patients with UGIH who may have a negative EGD can be identified prior to endoscopy.