Comparative findings concerning the effect of elenium and seduxen on the cardiovascular system
Raĭskiĭ, V.A.; Rozonov, I.B.; Chichkanov, G.G.
Zhurnal Nevropatologii i Psikhiatrii Imeni S.S. Korsakova 76(2): 282-286
1976
ISSN/ISBN: 0044-4588 PMID: 1266496 Document Number: 96271
The authors studied the effect of seduxen and elenium on 169 patients, particularly their pulse frequency, arterial pressure, electro- and polycardiogramms in a single administration of the drugs parenterally and in a long-term per os administration. A parenteral introduction of both drugs was accompanied by a slight bradycardial effect. However, high doses of seduxen (0.34--0.5 mg/kg) lead to states of tachycardia. Unlike elenium which did not exert a hypotensive effect, seduxen displayed a mild and in some cases significant hypotensive action.