Endotoxemia in typhoid encephalopathy
Nag, A.K.; Saha, K.; Mehrotra, A.N.; Ray, D.
Indian Journal of Medical Research 63(9): 1273-1279
1975
ISSN/ISBN: 0019-5340 PMID: 1222978 Document Number: 95853
Sera of 11 patients with typhoid fever were tested for the presence of endotoxin or endotoxin-like material by chick embryo assay. The endotoxin-like material was detected in all typhoid patients with encephalopathy, but not in uncomplicated cases. The sensitivity of the method was 0.032 .mu.g/ml of serum. This is comparable to the sensitivity of the epinephrine skin test but is less sensitive than the Limulus lysate technique.