Influence of non-H-2 genotype on the response to H-2-linked mixed lymphocyte reaction stimulating (MLR-S) genes
Rychlíková, M.; Démant, P.
Folia Biologica 21(1): 65-69
1975
ISSN/ISBN: 0015-5500 PMID: 123514 Document Number: 95833
The intensity of the mixed lymphocyte reaction (MLR) to H-2-linked MLR-stimulating genes is influenced by the non-H-2 genotype. The same H-2 incompatibility resulted in a stronger MLR when both partners had the C57BL/10ScSnPh genetic background than when they had the genetic background of the A/Ph strain. It is suggested that the intensity of the MLR to incompatibility for H-2-linked MLR-stimulating genes is controlled by MLR-response genes not linked to the H-2 complex.