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Pediatrics, medical research and the health of the children in Puerto Rico: Pessimism or crude reality?

Bonilla-Félix, M.

Boletin de la Asociacion Medica de Puerto Rico 95(1): 9-14

2003

ISSN/ISBN: 0004-4849
PMID: 12898745
Document Number: 9574
Neutropenia existe cuando el contaje absoluto de neutrofilos es menor de 1000/mm3 en infantes entre 2 semanas y 1 año de edad y menor de 1500/mm3 en niños mayores de un año. Infecciones severas ocurren cuando el contaje absoluto de neutrofilos es menor de 500/mm3, siendo mas común los abscesos perirectales, neumonía y sepsis. El factor estimulante de las colonias de los granulocitos (G-CSF) produce una recuperación sustancial de los neutrofilos en pacientes con neutropenia severa, reduce la incidencia y severidad de las infecciones bacterianas y mejora la calidad de vida de los pacientes. Varias citopenias incluyendo neutropenia, trombocitopenia y pancitopenia han sido reportadas en asociación con enfermedades del metabolismo de aminoácidos tales como acidemias methylmalonica, propionica e isovalerica. Nosotros describimos un infante con acidemia metilmalonica que presentó con neutropenia severa.

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Pediatrics, medical research and the health of the children in Puerto Rico: Pessimism or crude reality?

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