Pain-alleviating action of fentanyl and pentazocine in combination with droperdol and carbidine
Novikova, G.V.; Zorian, E.V.
Farmakologiia i Toksikologiia 38(5): 547-551
1975
ISSN/ISBN: 0014-8318 PMID: 1183584 Document Number: 91988
Tests staged on rabbits showd that analgesic (phentanyl and pentasocine), neuroleptics (droperidol and carbidine) and their combinations produce a more pronounced and analgesic action with an electric irritation of the dental tissues than with that of the rabbit's paw. Neuroleptanalgesic mixtures containing pentasocine display a somewhat weaker analgesic activity, but their effect lasts longer and they have a less marked influence on the respiration. Mixtures containing cabidine in lieu of droperidol produce a somewhat greater analgesic effect and relax and skeletal muscles less.