Induction of lesional and circulating leukocyte apoptosis by infliximab in a patient with moderate to severe psoriasis

Malaviya, R.; Sun, Y.; Tan, J.K.; Magliocco, M.; Gottlieb, A.B.

Journal of Drugs in Dermatology Jdd 5(9): 890-893

2006


ISSN/ISBN: 1545-9616
PMID: 17039656
Document Number: 9172
Infliximab demonstrates high efficacy in treating psoriasis in a high proportion of patients. In this report we demonstrate induction of plaque (T cells, dendritic cells) and peripheral blood (T cells, monocytes) leukocyte apoptosis following a single infliximab infusion in a psoriasis patient.

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Induction of lesional and circulating leukocyte apoptosis by infliximab in a patient with moderate to severe psoriasis