Is the prostatic adenoma of hormonal origin
Bercovici, J.P.; Morfin, R.; Charles, J.F.
La Nouvelle Presse Medicale 4(7): 475-478
1975
ISSN/ISBN: 0301-1518 PMID: 48234 Document Number: 91718
Prostatic adenoma develops at the site of the periurethral glands. The concentration of 5alpha-dihydrotestosterone seems greater at the center of the adenoma than in the overlying prostate. This suggests that medical treatment of prostatic adenoma might be feasible using substances inhibiting the 5alpha-reduction of testosterone.