Desmopressin tablet treatment: factors influencing gastrointestinal absorption

Rittig, S.; Jensen, A.R.; Jensen, K.T.; Pedersen, E.B.

Scandinavian Journal of Urology and Nephrology. Supplementum 183: 51-52

1997


ISSN/ISBN: 0300-8886
PMID: 9165607
Document Number: 906
The effect of food ingestion on the gastrointestinal absorption and antidiuretic action of oral desmopressin (Minirin, DDAVP) was assessed in 16 healthy volunteers, aged 20-35 years. The gastrointestinal absorption of desmopressin was reduced and delayed if administered with or 90 minutes after a meal, but this did not influence the antidiuretic action of the drug, at least for the first 3 hours following desmopressin administration.

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Desmopressin tablet treatment: factors influencing gastrointestinal absorption