Fluticasone-associated cutaneous allergic granulomatous vasculitis

English, J.; Greer, K.E.; McCrone, S.A.; Patterson, J.W.; VanLoock, J.S.

Journal of Drugs in Dermatology Jdd 2(3): 326-329

2003


ISSN/ISBN: 1545-9616
PMID: 12848118
Document Number: 8995
Allergic granulomatous vasculitis, or Churg-Strauss syndrome, is a small-vessel, multisystem vasculitis that can affect the skin, lungs, heart, and nervous system. Recent reports have implicated leukotriene receptor antagonists and inhaled corticosteroids in the development of this rare syndrome. We present a patient with no history of allergic asthma who acutely developed skin-limited Churg-Strauss-like granulomatous vasculitis after initiating therapy with inhaled fluticasone and salmeterol (Advair Diskus).

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Fluticasone-associated cutaneous allergic granulomatous vasculitis