Plasma transport of 5-hydroxytryptamine-3H. I. Nature and classification of indole derivatives after injection of 5-hydroxytryptamine-3H
Ollivier, Y.; Chauvel, Y.; Samperez, S.; Jouan, P.
Comptes Rendus des Seances de la Societe de Biologie et de ses Filiales 169(2): 408-412
1975
ISSN/ISBN: 0037-9026 PMID: 126776 Document Number: 89656
After a single i.p. injection of tritiated-5-hydroxytryptamine to young, old or stressed rats, the blood plasma was filtered through Sephadex-G 25 column. Two peaks of radioactivity were obtained. One was excluded from the column and eluted together with plasma proteins, the other was retained on the column and eluted as free indoles. The radioactivity bound to plasma proteins was identified as 5-hydroxyindole acetic acid. The free radioactivity was identified as 5-hydroxytryptamine.