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FISH - A New Noninvasive Method for the Diagnosis of Urinary Bladder Carcinomas

Lieselotte Lübbe; Nowack, R.; May, M.; Ullmann, K.; Gunia, S.; Kaufmann, O.; Hakenberg, O.; Muche, J.; Hoschke, B.

Clinical Laboratory 50(7-8): 395-402

2004

ISSN/ISBN: 1433-6510
PMID: 15330506
Document Number: 8956
Urinary bladder carcinoma is one of the most frequent malignant tumour diseases. The frequency increases with advancing age. The knowledge increase about genetic changes in tumour cells opens the possibility of a new noninvasive diagnosis with the help of fluorescence in situ hybridization (FISH). Comparable data are obtained by application of different diagnostic methods (fluorescence in situ hybridization, urinary bladder cancer ELISA, urinary cytology, histopathology) at different times from 6 coincidentally selected patients (preoperation, biopsy material and postoperation). The FISH test proved to be a sensitive method and correlated with the histopathological data.

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FISH - A New Noninvasive Method for the Diagnosis of Urinary Bladder Carcinomas

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