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Palliative treatment of metastatic breast cancer with diethyldioxystilbene diphosphate (Honvan)

Rosset, G.; Barrelet, L.; Alberto, P.

Schweizerische Medizinische Wochenschrift 105(43): 1388-1390

1975

ISSN/ISBN: 0036-7672
PMID: 1215912
Document Number: 89487
21 postmenopausal patients with skin or/and bone metastases of breast carcinoma received 100-120 mg daily diethyldioxystilbene diphosphate (Honvan) orally. 7 objective remissions were observed, 8 tumors remained unchanged, and 6 were progressive. In 3 cases, rapid tumor progression was suggestive of estrogenic stimulation. Side effects were the same as for other estrogens. Diethyldioxystilbene disphosphate is an active estrogenic compound in the treatment of breast carcinoma.

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