Evaluation of the VITROS 5,1 FS Chemistry System in a Large Pediatric Laboratory
Herkner, K.; Reiter, R.-Reisacher; Sonntag, O.
Clinical Laboratory 53(1-2): 17-26
2007
ISSN/ISBN: 1433-6510 PMID: 17323821 Document Number: 8928
The VITROS® 5,1 FS analytical system was evaluated. The measurement of the serum proteins and HDL cholesterol with the newly developed MicroTip technology was compared with other nephelometric and turbidimetric methods. The within-run imprecision for apolipoprotein A1, apolipoprotein B, complement 3, complement 4, transferrin, immunoglobulin A, immunoglobulin M, immunoglobulin G and HDL cholesterol showed coefficients of variation between 0.4% and 4.7%. The day-to-day imprecision showed coefficients of variation between 0.5% and 4.0%. The correlation with the comparative methods (nephelometric or turbidimetric) was good, with Pearson correlation coefficients of between 0.959 and 0.995. The comparison of apolipoprotein A1 showed a slope of about 0.76. An explanation for the difference could not be found. The VITROS 5,1 FS analytical system is a reliable routine instrument which fits into a large pediatric laboratory of a university.
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