Estimated glycolytic flux in infarcting heart
Opie, L.H.; Owen, P.; Lubbe, W.
Recent Advances in Studies on Cardiac Structure and Metabolism 7: 249-255
1975
ISSN/ISBN: 0363-5872 PMID: 131960 Document Number: 89265
Regional ischemia results in infarction even in the presence of residual oxidative metabolism. Although glycolytic flux is relatively inhibited at the level of phosphofructokinase, glucose competes more effectively than does free fatty acid for the residual oxygen supply. Glycogen is not the major energy source until effective collateral flow is virtually zero.
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